Articles on gluten intolerance

For RESEARCH REPORTS on gluten intolerance click here.

For general articles and research on coeliac disease, see here

For articles and research on the management of coeliac disease, see here.

For anyone who thinks they may be intolerant to grains other than wheat, barley and rye, or to all gluten in all grains, nutritonist Micki Rose's Truly Gluten Free site is a mine of information and an absolute 'must read'.

Her article, Gluten: No grain, no pain, here on the CM site, is a good introduction to why stopping wheat, rye and barley may not be enough to avoid gluten.

My fortnight with gluten. Although never formally diagnosed with coeliac disease, Catherine Rose has not eaten gluten for 10 years. Now she is to be tested but, for the test to mean anything, she has to go back to eating gluten for two weeks. This is her diary of those two weeks.... August 2017 And the results..... September 2017

The role of zonulin in gluten intolerance - helpful article in The Salt. December 2015

Alex Gazzola reviews a new article on Non Celiac Gluten Sensitivity – and concludes that we still understand very little about it. October 2015

Gluten Summit – the overview. Micki Rose pulls together the findings of the 2014 Gluten Summit. October 2014

Gluten Summit Speakers Series: 5
In this report, Micki Rose focused on advice from a leading clinical nutritionist, Dr Liz Lipski and a world authority on autoimmune disease, Dr Yehuda Schoenfeld. September 2014

Gluten Summit Speakers Series: 4
Micki Rose starts to look at the field specialists: the neurologists, paediatricians, immunologists and gastroenterologists at the clinical sharp end. First up: Dr Rodney Ford, gastroenterologist, paediatrician, gluten specialist; Dr David Perlmutter, neurologist, research scientist and Dr Daniel Amen, psychiatrist, brain imaging scientist. Augsut 2014

Gluten Summit Speakers Series: 3
For her third report Micki Rose focuses on Professor Marios Hadjivassiliou (neurologist, gluten ataxia and Gluten Related Disorders specialist) and Dr Umberto Volta (Cardiology, internal medicine, immunology, focus on gluten illness and malabsorption syndromes) August 2014

Gluten Summit Speakers Series: 2
For the second report Micki Rose focuses on immunology with Dr Aristo Vojdani who, because he had so much interesting stuff to say, gets an article all to himself. July 2014

Gluten Summit Speakers Series: 1
Micki Rose reports. First up: Dr Michael Marsh & Professor Alessio Fasano July 2014

Gluten Related Disorders: Our Knowledge Expands. Micki Rose reports on the e-summit organised earlier in 2014 by gluten-disorder specialist, Dr Tom O’Bryan, with twenty-nine of the world’s top gluten researchers and clinicians. June 2014.

Cross-talk between the gut and the brain: connections between gluten and autism via the leaky gut. Lecture by Dr Alessio Fasano on the Latitudes site. July 2014

Why are we all avoiding gluten? Following up on lengthy articles in the press about the stratospheric growth in the gluten-free market, Michelle Berriedale-Johnson has two suggestions. July 2014

Truly Gluten Free: Putting the jigsaw together. Inspired by the 'Grain of Truth' e-summit earlier this year, Micki Rose has developed a new 'Gluten Plan'. June 2014

Forum thread on the develpment of gluten intolerance post hysterectomy. May 2014

Changing attitutudes to gluten-free diets (in the US) as gf becomes more mainstream. Comment in the Huffington Post. March 2014

Could the introduction of genetically modified foods be relevant in the rising prevalence of gluten-related disorders? Jeffrey Smith of the Institute for Responsible Technology says ‘yes’. November 2013

Discussion on GreenMed Info as to whether gluten actually damages the human brain. November 2013

Understanding and managing non-coeliac gluten sensitivity – Professor David Sanders October 2013

What if your gluten intolerance is all in your head? Philosopher, Alan Levinovitz ask whether gluten intolerance, like an intolerance to MSG, could actually be the nocebo effect. July 2013

The Dietary Intake of Wheat and other Cereal Grains and Their Role in Inflammation. Evidence from in vitro, in vivo and human intervention studies that describe how the consumption of both wheat and other cereal grains, can contribute to the manifestation of chronic inflammation and autoimmune diseases by increasing intestinal permeability and initiating a pro-inflammatory immune response. March 2013

Clear analysis of the proteins and enzymes in wheat which fall outside the very narrow classic criteria for coeliac disease but which can still trigger the symptoms of gluten intolerance – and how to test for sensitivity. From Chris Kresser in the Huffington Post. April 2013

New enzymes may help those who are gluten intolerant. The enzymes help to break down the gluten proteins thus making them more digestible. March 2013

Cyrex Laboratories tests for gluten sensitivity. Article in the Townsend Letter by Dr Aristo Vojdani, Chief Scientific Advisor to Cyrex on the tests they offer for gluten sensitivity. February 2013

'Gluten-Free, whether you need it or not' – discussion piece in NY Times including interview with Dr. Stefano Guandalini, medical director of the University of Chicago's Celiac Disease Center, on non-coeliac gluten sensitivity. February 2013

Long article in the NY Times about a three-year-old whose juvenile idiopathic arthritis was entirely resolved by going gluten-free. February 2013

Gluten sensitivity biomarker coming soon. Interview on with Dr. Alessio Fasano who is confident that a clinical trial now underway at the Center for Celiac Research in Boston and the second University of Naples, will pinpoint a biological marker, or biomarker, for non-celiac gluten sensitivity, and that discovery should pave the way for the development of diagnostic tests for the condition.
If such a marker is identified it could help to clarify the controversial relationship between gluten sensitivity and autism and identify which autistic children might benefit from a gluten-free diet. January 2013

Portrait of a gluten-sensitive family. An interesting blog describing four generations of ultra gluten sensitivity. 2009–2011

A gluten for punishment: the whole grain assault on health
Lengthy blog on GreenMedInfo suggesting that alarge proportion of the US (and possibly the world) population may be sensitive to certain molecules present in most grain – and that those who belittle the gluten-free movement as a fad might, in fact, be unknowing victims of grain sensitivity. December 2012

Does gluten sensitivity in the absence of coeliac disease exist? Article in the BMJ by Drs Aziz and Hajivassiliou and Professor David Sanders giving an honest account of gluten sensitivity, recognising the limitations of medical testing and admitting that there are things we simply don't know or understand. Helpful comment on Dr John Briffa's blog.November 2012

Non-coeliac gluten sensitivity – a lengthy correspondence in the BMJ between a gluten sensitive who spent 20 years getting progessively sicker and being repeatedly misadiagnosed (interstital cystitis, gall bladder) before a chance conversation on a forum suggested that he should exclude gluten and lactose from his diet, with dramatic results. Comments from consultant physician Dr Kamran Rostami. November 2012

10 good reason to give up gluten from 'Grass Fed Girl' . November 2012

Barrier Breakdown: The Cause of Multiple Sensitivity? Nutritionist Micki Rose explains her theories about barrier breakdown in multiple sensitivity and how she believes the barriers can be repaired. June 2012

How to respond to those who criticise the totally grain-free diet. July 2012

The gluten and grain-free nettle beer that the government wants to call wine! Sue Cane reports. April 2012

How gluten causes coeliac disease. Lengthy blog post explaining in detail, but in layman's terms, the precise mechanisms involved in the autoimmune condition and suggesting that getting rid of gluten may not be enough. February 2012

How a gluten-free diet helped to free me from IBS. It took Sophie Lee fifteen years to link her IBS to gluten – but since she did, she hasn't looked back. And now she has written a book about it. January 2012

Gluten illness, malabsorption and finding the key. Excellent post on the Truly Gluten Free site on how severe gluten intolerance can prevent the absorption of nutrients with all the ill health that can entail. January 2012

Residual gluten proteins found in wine that has been clarified with wheat gluten. The research report – and comments. December 2011

Helpful article in Natural News on supplements and herbs you can take to promote gut healing as a newly diagnosed coeliac/gluten intolerant. December 2011

Travelling gluten-free in Wales. Blog post describing a very successful gluten-free Welsh holiday. October 2011

Corn-free pain killers. An helpful post on the TrulyGlutenFree site about pain killers delivered as suppositories and thus totally gluten free. July 2011

Gluten intolerance on the rise in China and the Far East. Until recently gluten intolerance and coeliac disease were all but unknown in China but an article in the South China Morning Post suggests that this is changing. July 2011

Gluten sensitivity – what exactly is going on? An excellent post by Micki Rose on her Truly Gluten Free site on the progressive damage caused by gluten to those who are sensitive to it. July 2011

Grain and Corn Free Supplements: A Nightmare! Micki Rose explains why and what you can do about it. May 2011

Gluten: No grain, no pain. Nutritionist Micki Rose lifts the lid on why stopping wheat, rye and barley may not be enough to avoid gluten. February 2011

Gluten-free beer. How is it made? How is its gluten content tested? And is it really safe for coeliacs? Sue Cane investigates. January 2011

Professional cyclists go gluten-free. February 2010

Lucy Cooks Cookery School: some instruction into gluten-free cookery in the Lake District, by Laura Lebetkin. December 2008

Micki Rose's low glycaemic load, gluten-free, dairy-free diet: fed up with continually cobbling together diets for her food sensitive patients, she has finally written a diet plan. July 2008


NB Information on this site is not a substitute for medical advice and no liability can be assumed for its use.

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Research reports on gluten intolerance

For links to gluten-free food products click here.
For links to gluten-free skincare products click here.

Non-celiac gluten sensitivity: people without celiac disease avoiding gluten - is it due to histamine intolerance? Nov 2017
Interesting article highlighting the similarities between the symptoms of non-coeliac gluten sensitivity and histamine intolerance, together with thoughts about what this might mean for treatment.

The Overlapping Area of Non-Celiac Gluten Sensitivity (NCGS) and Wheat-Sensitive Irritable Bowel Syndrome (IBS) Nov 2017
An interesting (full-text) review article exploring the current research into Non coeliac Gluten Sensitivity and overlapping conditions. Issues such as prevalence of the condition and why gluten can cause such adverse reactions are deliberated.

Non-coeliac gluten sensitivity. March 2017
Gluten sensitivity in individuals without coeliac disease is now widely reported but we still know little about the mechanisms underlying this sensitivity. This review article explores some of the possible underpinning factors and reveals how little we still know about the diagnosis, causes, therapeutic approaches and outcomes for patients with non-coeliac gluten sensitivity. 

Is there a relationship between gluten sensitivity and postural tachycardia syndrome? (Abnormal increase in heart rate that occurs after sitting up or standing causing dizziness or fainting) Dec 2016 (Epub ahead of print)
This study found a higher incidence of both coeliac disease and self-reported gluten-intolerance in patients with postural tachycardia syndrome (PoTS). It is the first study to propose a relationship between gluten sensitivity and PoTS, suggesting future research into the co-occurrence of these conditions is necessary.

Long-term response to gluten-free diet as evidence for non-celiac wheat sensitivity in one third of patients with diarrhea-dominant and mixed-type irritable bowel syndrome. Sept 2016
Around one third of patients with Irritable bowel syndrome (IBS) saw a significant improvement in symptoms on a gluten-free diet.

Evidence for the Presence of Non-Celiac Gluten Sensitivity in Patients with Functional Gastrointestinal Symptoms: Results from a Multicenter Randomized Double-Blind Placebo-Controlled Gluten Challenge. February 2016

The neurological manifestations of CD and NCGS are similar and equally responsive to a GFD suggestive of common pathophysiological mechanisms. February 2016

From coeliac disease to non-coeliac gluten sensitivity; should everyone be gluten free? March 2016

Non-celiac wheat sensitivity: differential diagnosis, triggers and implications. June 2015

The overlap between Irritable Bowel Syndrome and Non-Celiac Gluten Sensitivity: a clinical dilemma. December 2015

High levels of zonulin linked to NCGS and IBS. October 2015

Responses of peripheral blood mononucleated cells from non-celiac gluten sensitive patients to various cereal sources. June 2015

Data indicate that many adult Australians are consciously avoiding consumption of wheat foods, predominantly without any formal diagnosis. Reported symptoms suggest a physiological but not allergenic basis to this behaviour. February 2015

Prospective survey shows that NCGS has a strong correlation with female gender and adult age but the prevalence of NCGS seems to be only slightly higher than that of celiac disease. May 2014

A review of the most recent findings on Non Celiac Gluten Sensitivity and directions to dissipate some of the confusion related to this disorder. May 2015

Gluten-free diet reduces risk of type 1 diabetes in mice. May 2014

Gluten sensitivity in children mirrors features of adult GS. March 2014

Could glyphosphate be implicated in the rise in gluten diseases? Comment here. February 2014

Non-coeliac wheat sensitivity may be a food allergy. November 2013

A subset of children with autism displays increased immune reactivity to gluten, the mechanism of which appears to be distinct from that in celiac disease. June 2013

Gluten-related disorders associated with demyelinating diseases such as multiple sclerosis and neuromyelitis optica. April 2013

Wheat and other cereal grains and their role in inflammation and autoimmune disease March 2013

Massive increase in use of 'vital' gluten and wheat flour over last 40 years. February 2013

Gluten-free diet successful for those with NCGS. February 2013

Non-celiac wheat sensitivity diagnosed by double-blind placebo-controlled challenge: exploring a new clinical entity. December 2012

Gluten-free diet can help those with demyelinating diseases such as MS, as well as those who are gluten sensitive. September 2012

Gluten causes gastrointestinal symptoms in subjects without coeliac disease although there is little understanding of the mechanisms. March 2012

Blood pressure drug linked to gluten sensitivity-like symptoms. June 2012

Gliadin allergy manifested with chronic urticaria, headache and amenorrhea.  December 2011

Specific carbohydrate diet. A pilot study at the University of Massachusetts Medical School shows significant success with Inflammatory Bowel Disease. The abstract for UMMAS is here and the comment here. May 2011

Organisms in saliva may play a role in breaking down gluten. October 2010

Gluten in red wine. July 2011

Significant differences identified between coeliac disease and gluten sensitivity.
March 2011

Could tissue transglutaminase be the autoantigen in most diseases and how could this be related to a gluten intolerance? December 2010

Gluten sensitivity and the brain. November 2010

Sensory ganglionopathy may respond well to a strict gluten-free diet.
October 2011

Apraxia appears to be linked to food allergies, gluten sensitivity and nutrient malabsorption. July 2009

Eating gluten again? June 2009

FSA - Codex standard. December 2008

Age of gluten exposure impacts development of coeliac disease. November 2008

Pilot study supports the hypothesis that gluten elicits its harmful effect, throughout an IL15 innate immune response, on all the individuals. This innate response is found in both patients with and without CD, although the triggering of an adaptive response is CD specific. June 2007


Articles on gluten intolerance



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If you found this article interesting, you will find many more general articles and research reports on coeliac disease here, and lots of information on the management of coeliac disease here.
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