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Leaky Gut Syndrome |
Leaky gut syndrome is often cited as an important factor in food allergy and intolerance but what exactly is it and is it really relevant? Several Foods Matter readers have asked us this question so we thought we would ask Dr Alan Stewart, widely known for his work on nutrition and food sensitivity. For in-depth information on nutrition, consult his website at www.stewartnutrition.co.uk. |
Leaky gut syndrome (LGS) has become a popular diagnosis which has considerable credence in the popular media but has few friends in conventional medical circles. Recent evidence, however, suggests that it does exist and can be easily caused by use of acid-suppressant drug therapy. Its clinical significance is still debated. Mechanisms The part played by bowel flora is not at present clear. Changes in flora could alter the function of enterocytes, their adhesion and, of course, gut transit as well as the production of undesirable immune and inflammatory effects. It does seem that there is renewed interest in the function of the gut wall in many gastrointestinal and other diseases. LGS may be a reality for some patients but its importance is as yet unclear. Whether adding this diagnosis to an exisiting gastrointestinal one is of benefit to the patient is also unclear. A degree of healthy scepticism should be combined with a little optimistic interest when considering LGS. References 1 Millward C. et al. Gluten- and casein-free diets for autistic spectrum disorder. Cochrane Database Syst Rev. 2008 Apr 16;(2):CD0033498. Margaret Moss comments: Click here for more articles on digestive conditions First Published in 2009 |
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